Is Masseter Botox Worth It? We Asked 8 People for Their Honest Reviews – Lose Weight in Your Hips

If you regularly wake up with a sore jaw, chances are you’ve come across masseter Botox as a possible remedy. Yep, even though botulinum toxin (the scientific name for Botox, if you didn’t know) is most known for its ability to temporarily smooth facial wrinkles, it’s got some research-backed medical benefits, too. Basically, these injections … Read more

Inhibiting P16 in Microglia Reduces Amyloid Plaques in Mice – Fight Aging!

Researchers here show that targeting microglia in a mouse model of Alzheimer’s disease to suppress p16 expression can reduce amyloid-β plaques. This appears to be a way to interfere in a maladaptive reaction to amyloid-β on the part of microglia, innate immune cells responsible for clearing molecular debris from brain tissue. P16 is a … Read more

Further Considering the Altered Transcription of Longer Genes with Age – Fight Aging!

Further Considering the Altered Transcription of Longer Genes with Age The machinery of gene expression changes with age. In recent years, it has been noted that the length of gene sequences correlates with the degree to which transcription of gene sequences into RNA molecules changes over the course of aging. Later work has started … Read more

3 Major Abortion Pill Myths to Be Aware of Right Now – Lose Weight in Your Hips

“The abortion pill remains unnecessarily over-regulated,” Ashley Jeanlus, MD, ob-gyn and assistant professor at the University of California, San Francisco’s Bixby Center for Global Reproductive Health, tells SELF. She says the initial label changes made by the FDA in 2016, including the increase of the gestational age limit to 10 weeks, were “consistent with medical … Read more

Loss of Anti-Microbial Peptides as a Mechanism for Age-Related Changes in Gut Microbiome Composition – Fight Aging!

The balance of microbial populations making up the gut microbiome changes with age in ways that are damaging to long-term health. Firstly the proportion of pro-inflammatory microbes grows, provoking the immune system into greater degrees of unresolved inflammation. This state of inflammaging observed in older individuals is disruptive to tissue structure and function throughout … Read more

How to Be a Genuinely Good Listener – Lose Weight in Your Hips

Kelaher suggests phrases like, “If I’m hearing you correctly…” and “If I’m getting this right…” For example, “So if I’m understanding, this promotion has been way more stressful than you anticipated?” Then, once you summarize and ensure you’re on the same page, you can add some validation, too. “Ugh, it’s so tough when something you … Read more

Exercise Might Be the Natural Sleep Aid You’re Seriously Overlooking – Lose Weight in Your Hips

In general, aiming for the government guidelines is a worthwhile goal if you want to reap many of the health benefits of exercise, including better sleep, Dr. Kline says. But don’t stress if that feels like a lot: It’s likely that smaller amounts help, too. More research is needed—some of which is already underway—on whether … Read more

More Commentary on the Role of PF4 in Reducing Brain Inflammation – Fight Aging!

Platelets in the blood are not just involved in clotting. Near every aspect of our biology has evolved many different functions, and the complexity of our biochemistry is still far from fully explored. Increased platelet factor 4 (PF4) shows up as a feature in a number of different interventions known to reduce inflammation in … Read more

11 Best Waterproof Hiking Boots in 2024, According to Experts – Lose Weight in Your Hips

Most Protective Pros: Very durable, designed for trekking and long hikes Cons: Heavy If you’re taking on an especially long, difficult trail or embarking on a backpacking trip, the Salomon Quest 4 is the rugged boot you need. It has a range of tough features like aggressive lugs, a thick rubber outsole, a toe cap, … Read more

Lipid Droplets in Microglia Involved in Alzheimer’s Pathology – Fight Aging!

Lipid Droplets in Microglia Involved in Alzheimer’s Pathology Microglia are innate immune cells resident in the central nervous system. Microglial dysfunction is clearly a contributing factor in the onset and progression of age-related neurodegenerative conditions, including Alzheimer’s disease, as well as the accompanying chronic inflammation of brain tissue. As to why microglia become problematic … Read more